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Experimental analysis of the solubility of glycerol and MK2866

11 Jun,2025

In the series of MK-2866 solubility tests, glycerin takes the stage as the final solvent to be examined.

As usual, we began the solubility test with 1 ml of glycerin. However, right from the start, we encountered some unique challenges—glycerin's extremely high viscosity made the dissolution process unusually slow. In hopes of giving the compound more time to dissolve, we let the mixture sit undisturbed for a while. Unfortunately, even after a significant waiting period, there were no visible signs of dissolution.
1 1ml result

When Letting It Sit Doesn't Work: Increasing the Glycerin Volume

To further assess glycerin's solubility potential, we boldly adjusted the experiment by increasing the volume directly to 20 ml, followed by thorough stirring. The resulting mixture turned into a milky, opaque liquid—a red flag for anyone familiar with solubility testing. For those who've followed our experiments closely, you'll know: a milky, cloudy solution often indicates poor solubility. To confirm this, we examined the solution in greater detail.

Experimental Findings and Observations

A closer look inside the beaker revealed that a large amount of MK-2866 powder was simply wrapped in glycerin, sticking to the beaker walls in clumpy, undissolved masses. This clearly showed that MK-2866 hadn't truly dissolved in the glycerin, but rather existed in a suspended or adhered state.
2 20ml result

Conclusion: Glycerin is Not a Suitable Solvent for MK-2866

Based on the experiment, we can draw a clear conclusion: glycerin is not an ideal solvent for dissolving MK-2866. While its high viscosity might benefit the dissolution of certain compounds with lower solubility demands, it simply fails to effectively dissolve powdered compounds like MK-2866. So yes, we've eliminated another solvent from the list.
3 conclusion

Looking Ahead

Although glycerin didn't perform well in this test, a failed experiment is still valuable knowledge. At the very least, we've helped you rule out one more option—right?

While glycerin cannot fully dissolve MK-2866 powder in this case, it remains a highly versatile substance with wide applications in pharmaceuticals, food, cosmetics, industry, and agriculture. Its low toxicity, eco-friendly nature, and chemical stability make it a staple in many products and processes.

As for MK-2866, glycerin might not work as a primary solvent—but perhaps with additional methods, such as heating or the use of co-solvents, its potential could still be tapped in some form.