Solubility Test of MK-2866 (Ostarine) in PEG400

Now it’s time to test how well PEG400 can dissolve MK-2866. Are you looking forward to the results? Let’s jump straight into the experiment and see what happens step by step.

Experimental Procedure

1 ml
We always start with 1 ml as the standard initial volume. Using a dropper, we add 1 ml of PEG400 to 1 gram of accurately weighed MK-2866 powder.
And the result? There’s no obvious sign of dissolution.

5 ml
Since PEG400 is quite viscous, increasing to just 2 ml probably won’t make much difference.
So we go ahead and increase the volume directly to 5 ml, followed by thorough stirring.
Now the mixture turns into a milky-white paste. Still, no clear sign of dissolution.

It seems that MK-2866 doesn’t dissolve in PEG400 as well as we had hoped. So what’s next? Let’s jump to 10 ml and see how it performs.

10 ml
Alright, with 10 ml added, the solution looks a little clearer compared to the 5 ml test.
That’s a good sign—it indicates partial dissolution.
There’s hope! As long as we add enough solvent, MK-2866 should fully dissolve eventually.
20 ml

20 ml
This time, we increase the volume to 20 ml, again stirring thoroughly.
Look! The solution is becoming noticeably clearer. This supports our earlier assumption.
Upon closer inspection, there are still some undissolved MK-2866 particles at the bottom, indicating we need even more solvent.

Based on previous experience, let’s try 30 ml.
Now the big question: Can 30 ml of PEG400 fully dissolve 1 gram of MK-2866 powder? Do you believe in it?

Time to reveal the answer: The solution turns completely clear and transparent.
What does this mean? If you’ve been watching our experiments, you already know—this is the sign of full dissolution.
So yes, it takes 30 ml of PEG400 to fully dissolve 1 gram of MK-2866.

Result Analysis

Solubility Performance:
PEG400 does have the ability to dissolve MK-2866 powder, but the process is slow and requires a relatively large volume of solvent. In the end, 30 ml of PEG400 is needed to fully dissolve 1 gram of MK-2866.

Dissolution Observation:
As the volume of PEG400 gradually increases, the solution transitions from a milky paste to a clear liquid, showing that solubility improves with cumulative solvent volume.

Impact of Viscosity:
The high viscosity of PEG400 slightly hinders the dissolution process, requiring more time and a larger volume to achieve full solubility.

Conclusion

In this experiment, we confirmed that 30 ml of PEG400 can completely dissolve 1 gram of MK-2866 powder. Although the dissolution process is slower and less efficient compared to other solvents, the final concentration—30 mg/ml—is suitable for practical use. Considering MK-2866’s typical dosage for muscle-building purposes in bodybuilding, this concentration is quite usable.

Therefore, PEG400 is a viable option for individuals looking to prepare their own MK-2866 solutions.