Solubility Test and Evaluation of MK-2866 in DMSO

In this round of solvent testing, DMSO (Dimethyl Sulfoxide) was introduced as the fifth candidate solvent. Known as a “universal solvent” due to its exceptionally strong dissolving power, DMSO can dissolve a wide range of organic and inorganic compounds, making it one of the most commonly and widely used solvents in laboratories. But how well does it perform in dissolving 1 gram of MK-2866 (Ostarine)? Let’s explore the answer through this experiment.

Initial Test: 1ml DMSO
The experiment began with the addition of 1ml of DMSO. Within a short period, visual observation showed that the MK-2866 powder began to dissolve rapidly, with the solution’s clarity significantly increasing. Impressively, just 1ml of DMSO was enough to dissolve more than half of the powder, demonstrating its powerful solubility. This initial result clearly indicated DMSO's high efficiency as a solvent. To completely dissolve the remaining powder, more solvent was added.

Further Test: Increased to 2ml
Building on the success of the first step, we added another 1ml of DMSO, bringing the total to 2ml. After a brief stirring, the solution became fully clear and transparent, with all the powder completely dissolved—no residue or suspended particles remained. This completely transparent state is a clear indicator of successful dissolution, confirming that DMSO can dissolve MK-2866 very effectively with minimal volume.

Experimental Results and Analysis
Based on this experiment, the following conclusion can be drawn: DMSO can completely dissolve 1 gram of MK-2866 using only 2ml of solvent, demonstrating outstanding solubility. This makes DMSO one of the best-performing solvents for MK-2866, sharing the top rank with PG300 from previous tests.

Why Does DMSO Perform So Well?

Polarity: DMSO is a highly polar solvent. Its molecular structure enables it to effectively disrupt intermolecular forces, thereby facilitating dissolution.

Broad Compatibility: DMSO is miscible with water, alcohols, oils, and many other substances, allowing it to dissolve a vast range of compounds.

Molecular Penetration: DMSO has excellent penetrative ability, which allows it to rapidly come into full contact with MK-2866 powder and accelerate the dissolution process.

Conclusion and Comparison
Among all the solvents tested so far, DMSO stands out for its exceptional dissolving power—completely dissolving 1 gram of MK-2866 with just 2ml. It ranks alongside PG300 at the top in terms of solubility performance. This provides an efficient and reliable solution for users who need to dissolve MK-2866.