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Introduction and Cleaning of the GPCRMS Laboratory Reactor

17 Apr,2025

I’d like to introduce the reactor we use in our laboratory. It has a volume of 100 liters—not very large, but just the right size for our lab. It meets the needs of our daily research and development activities, while also being easy to operate and maintain. Our lab mainly focuses on the development of new synthetic routes and the optimization of existing processes, so this medium-sized reactor is very practical for our work.

Clean reactors 1

Today, this batch of reactors has just completed the last round of experiments and hasn’t been cleaned yet. So, we’d like to take this opportunity to demonstrate how we usually clean these reactors. Cleaning is a crucial part of reactor maintenance, as any residue from previous reactions can affect the accuracy of subsequent experiments and may even cause hazardous reactions.

Clean reactors 2

Before we begin cleaning, we prepare a suitable amount of neutralizing agent and cleaning solvent. As you can see, we use this white hose to transfer the cleaning liquid from the white bucket into the reactor by creating a negative pressure difference. This method is simple to operate and effectively controls the flow rate, preventing spills or overfilling.

This time, the residue inside the reactor is an acidic compound, so we need to add an appropriate amount of alkaline liquid to neutralize it. This ensures that the pH of the contents is within a safe range before disposal. After neutralization, we rinse the reactor several times with water until there are no visible residues or odors remaining. The entire cleaning procedure follows standard operating protocols, ensuring safety and preparing the reactor for the next round of experiments.

Clean reactors 3

By maintaining our equipment regularly and systematically, we not only extend its service life but also enhance the reproducibility and reliability of our experiments. We hope this brief demonstration gives you a clearer understanding of the workflows in our laboratory.